The principal function of ASTEXPECT's solution is that of a strong natural Peruvian expectorant, indicated for the infections of the respiratory low tract as the cough, bronchitis, asthma and pneumonia. It helps to eliminate the secretions of the trachea and the bronchi. This ASTEXPECT's solution must be taken during the nights, before going to bed. This solution has two principal effects:
1) Fluidify the phlegms of the cough or secretions; and,
2) To help eliminate the phlegms of the cough or secretions (natural Peruvian expectorant) across arcades, principally for the mouth.
This way, this ASTEXPECT's solution can destroy the different chemical - physical structures of the bronchial secretion, obtaining a decrease of the viscosity and, of this form, an easy and prompt elimination of the secretion. As corollary of the effect of this solution, we have the following indications or prescriptions that we can recommend: Elimination of the cough of any kind, gradual elimination of the secretion lodged at the trachea or at the bronchi; relief of the respiratory problems; to diminish the cooling of the patient, etc.
With ASTEXPECT you have a natural treatment of asthma, treatment to the asthmatic assault, treatment of the bronchial asthma, treatment of the asthmatic crisis, treatment of the infantile asthma and treatment of the chronic asthma
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a) Normal formation of the Bronchial Mucosity:
The mucosity normally is generated by the bronchial glands and the surface epithelium, lodging at the bronchi. It is constituted by 95 % of water and 5 % of solid. The solid principal ones are: Carbohydrates (sugar and starches), proteins, lípidos and DNA. The DNA originates from the remains of the leukocytes, macrófagos and cells of the bronchial epithelium.
The bronchial glands are a part of the defenses of the bronchi against the pathogenic agents. They produce acid gluco-protein, which serves to increase the viscosity of the fluids, as protective and lubricating cap.
b) Formation of the Bronchial Mucosity Falls ill:
From the fisio-pathological point of view, the patient on having fallen ill of the respiratory tract of the low tract, perspires very much and generates phlegms of the cough or secretion or bronchial mucosity contaminated with bacteria, germs virus, etc., producing to an inflammation that reduces the bronchi and reduces the level of revenue of the air to the lung, also dehydration and a cooling of the human body, which produces a major reabsorption of water to level of the bronchial epithelium, increasing of this form the viscosity of the secretion and impeding itselimination.
According to the degree of disease, the bronchial conduits will catch fire producing a major mucosity and edema in the bronchi, being simple in the cough, increasing in the bronchitis, becoming closer much more in the asthma and almost closing the conduits in the pneumonia, concerning the lungs.
Nowadays, have been recognized a series of bacteria that originate this bronchial inflammation, as it is the degree of the disease. This way we have that, when the patients are sick with savage cough, the mucosity is accompanied of the bacterium Bordetella pertussis. In case of bronchitis; of virus, bacteria and specially, for gérmenes similar to the bacteria, as Mycoplasma pneumoniae and Chlamydia.
In case of the asthma, it is believed that the fattened cells are those that originate the tightening. These are distributed in the bronchi and liberate substances as the histamine and the leucotrienos, which cause the contraction of the muscle and stimulates this way the increase of secretion of the mucosities. And finally, in case of pneumonia, the mucosity is accompanied of gram-positive bacteria, being the most important the pneumococcuses (80%), estafilococos and estrepcocos.
And, between the the most negative, the the most frequent, they are the hemophilus and klebsiellas. These phlegms of the cough or secretions are a mixture of plasma, water, electrolytes and mucina. As the above mentioned secretions cross the low and top routes, they contaminate with cellular defoliations, nasal secretions, with the salivary glands and the normal intestinal flora of the oral cavity. The snot possesses 95% of water and 1% of charcol hidrates, proteins, lipids, and inorganic material. Besides the water, the principal components are the mucos polisacáridos.
Between its physical properties the viscosity and elasticity stand out. Its consistency depends principally on the molecular structure of the gluco-proteins and on the degree of hydration. The acid siálico is the one that contributes of more important form to the viscosity of the saliva. The patients with bronchitis and asthma can have rough spasm (to produce secretions that reduce the flows and debilitate the process of cough). When coughing, is observed that the bronchi collapse, obstructing sometimes completely the airway or bronchial conduit, which makes feel to the patients a sensation of suffocation.
When the present disease is a pneumonia, the acid siálico can be destroyed by the neuroaminidasa or alter its load to a lower PH, diminishing the viscosity. The neuroaminidasa comes from the pneumococcuses and can serve to destroy the residues of acid siálico of the mucous bronchial ones and manages to liquefy the protective cap, making the cellular surface exposed to the pollution of inert particles or microorganisms.
c) Process of liquefaction of the secretion:
The medicinal effect of the solution on the patient is it of descongest, responses between the epistle gradually, the phlegms of the cough or bronchial secretions (phlegm, snot, mucosity) for the antiinflammatory effect of the active component, flavonoides, helping to diminish the edema of the mucous one, the excitability, which gives origin to the reflex tusigen, accompanied of a fever that does not pass from 38º. This effect happens from the first night of ingestion of the solution, producing an natural expectorant effect on the following and like that day successively improving day after day the permeability and pulmonary ventilation. At the same time as it helps eliminate the secretions as saliva, also it develops an antibacterial activity on the secretion, eliminating the bacteria. The consumption of this natural solution helps increase the defenses of the patient and, in consequence, to improve their health fast.
The liquefaction of the secretions is generated for the bitter beginning of the solution, wetting the respiratory low tract, reducing the elasticity and viscosity, liberating and liquefying the secretion, making it now ready to be evacuated by process of the effect natural expectorant. From a point of view physicist - chemist, the solution can destroy the different chemical - physical structures of the bronchial secretion, obtaining a decrease of the viscosity and, of this form, an easy and prompt elimination of the phlegm of the cough or secretion. The fluidificación of the phlegms of the cough or secretions also they are supported by the antibacterial action of the flavonoides, eliminating them and spending them to form a part of the secretion increasingly fluid and innocuous.
This process sensitizes the mucous ones of the larynx and of the tree traqueo bronchial, which generates a mechanical deformation and a chemical irritation, which causes a stimulus that moves rapidly in central direction up to the vocal chords and, generating this way, a tusigen reflex.
One of the irresolute elements is the sialic acid, that is an acid sugar which formula is derived from the acid of the N-acetilmanosamina called acid N-acetilneurominico (sialic acid), is present in many glico-proteins and glico-lipids. The principal characteristic of this acid is to generate a viscosity of the secretion with the walls of the bronchi. This acid on having put in touch with the flavonoides breaks, reducing its viscosity and the snot being liquefied by water increase that enters its molecular structure.
d) Expectorant process of the Saliva:
The process happens for the effect of ASTEXPECT's solution, that on having taken it in the nights before going to bed, natural expectorant produces an effect the following day of the secretion or saliva lodged at the respiratory system by effect of its active beginning known as the saponines.
The process natural expectorant or of cough it begins with a mechanism excitatory in the mucous irritated bronchial one, moving this excitation to the top centers of the cranial encephalon across the nerves neumogástricos; stimulating a reflex tusígeno.
This excitation generates a movement of the phlegms of the cough or secretions, crossing all the low routes of the respiratory tract, contaminating in the way with cellular defoliations, nasal secretions, secretions of the salivary glands and normal intestinal flora of the oral cavity. This mixture of secretions and particles receive the name of saliva.
On the reflex having be stimulated tusígeno, a phase strikes inspiratoria, adducing of the vocal chords and an energetic contraction of the abdominal muscles and intercostal; a pressure being generated this way intra-torasic of 40 cm. of water followed by a rapid opening of the glottis. In this instant, the great intra-pulmonary pressure produces a rapid expulsion of air that drags the secretion towards the biggest bronchi, the trachea and laryngeal structures. The secretions in the normal adult, reach a volume it is between 10 and 100 ml per day.
The saliva consists of snot (coming of mucous and serous cells of the bronchial glands and cells caliciformes), liquid trasudado of the fabrics, saliva, cellular material, enzymes and immunoglobulin. The snot possesses 95 % of water and 1 % of hidratos of carbon, proteins, lípidos, and inorganic material. Besides the water, the principal components are the mucos polisacáridos.
In the saliva also there are situated enzymes, immunoglobulin, cellular material (cells epiteliales flaked off), macrófagos alveolar, leukocytes polimorfos nuclear, whose fragmentation liberates ADN's small quantities. The presence of the Ion hydrogen can contribute to the antimicrobial properties of these components and affect the ciliary movement. The cilias cannot move with efficiency a minor PH of 6,5.
